The Syncytium

Diabetic cardiomyopathy is a heart condition caused by diabetes. Diabetes causes many changes throughout the body including how the heart makes energy. This energy change in the heart is due to hyperlipidemia which is a definitive characteristic of diabetes. Hyperlipidemia simply means there are too many fatty acids in the blood circulation. Fatty acids are…

This book imparted a series of invaluable lessons once I started reading it through a dynamic lens. Instead of reading about the elements of what makes a startup evolve into a successful company, I read the book as if Peter was talking about how a person builds a successful career. So when the book asked…

Follow the calcium. – cardiomyocyte calcium handling quick notes Big Picture: Calcium is responsible for the inotropic effect by facilitating the formation of cross-bridges between the myosin heads and the actin filaments. Depolarization induced calcium release. L-type calcium channel (DHP channel) activation causes calcium influx into the cardiomyocyte.  This is the same L-type calcium channel…